About Dissolving Dermal Fillers

In aesthetic medicine, hyaluronidase is used to dissolve dermal fillers that have been placed incorrectly, excessively, or unevenly. To remove fillers, hyaluronidase is injected to dissolve the hyaluronic acid in dermal fillers. The action of hyaluronidase is very quick and starts to work immediately on the dermal fillers. The fillers are permanently dissolved and metabolised. Note that hyaluronidase does not work on permanent or semi-permanent dermal fillers.

Who is this for?

Male and female who is unhappy with your dermal filler results or wish to reverse facial fillers.

When it’s not suitable?

Most patients will be fine to undertake dermal fillers injection, however, in certain circumstances,  dermal fillers are not recommended:

  • If you are pregnant or breastfeeding
  • If there is active skin inflammation or infection in or near the areas  


Hyaluronidase 1500 I.U.

Best Practices


Avoid alcohol consumption before the treatment to prevent bruising.



No rubbing or massaging of the injected area for 24 hours after treatment.

No strenuous exercise and sauna for 24 hours after treatment.

Wait at least 24 hours after injection before consuming alcohol. Avoid spicy food and seafood.

Stay well hydrated by drinking water.

Frequent Questions

Hyaluronidase does not work on permanent or semi-permanent dermal fillers. i.e. Ellanse and Radiesse.

The common brands of hyaluronic acid fillers that can be dissolved are:

  • Juvederm
  • Restylane
  • Stylage
  • Belotero
  • Teosyal

The common side-effects from hyaluronidase are swelling and bruising at the injected part.

A patch test can is recommended before the procedure. The practitioner will inject a small amount of Hyaluronidase at one of your arms. You will need to wait for 30 minutes to see the results of the patch test. The common sign of allergic reaction is swelling, rash, and redness at the injected part.